학술논문
Application of digital holographic and fluorescence microscopy for investigation of live cells response to photodynamic treatment using Radachlorin photosensitizer
Document Type
Conference
Author
Source
2020 International Conference Laser Optics (ICLO) Laser Optics (ICLO), 2020 International Conference. :1-1 Nov, 2020
Subject
Language
ISSN
2642-5580
Abstract
In this paper we present analysis of living cells response to photodynamic treatment. Intracellular generation of reactive oxygen species was performed by means of Radachlorin photosensitizer. Radachlorin accumulation in cells was controlled using fluorescence microscopy. Digital holographic microscopy was applied for monitoring cells response to photodynamic treatment at different doses. The results obtained can be used for estimation of cells resistivity to intracellularly generated reactive oxygen species.