부산대학교 도서관

Neonatal seizures are sudden events in brain activity with detrimental effects in neurological functions usually related to epileptic fits. Though neonatal seizures can be identified from electroencephalography (EEG), this is a challenging endeavour since expert visual inspection of EEG recordings is time consuming and prone to errors due the data’s nonstationarity and low signal-to-noise ratio. Towards the greater aim of automatic clinical decision making and monitoring, we propose a multi-output Gaussian process (MOGP) framework for neonatal EEG modelling. In particular, our work builds on the multi-output spectral mixture (MOSM) covariance kernel and shows that MOSM outperforms other commonly-used covariance functions in the literature when it comes to data imputation and hyperparameter-based seizure detection. To the best of our knowledge, our work is the first attempt at modelling and classifying neonatal EEG using MOGPs. Our main contributions are: i) the development of an MOGP-based framework for neonatal EEG analysis; ii) the experimental validation of the MOSM covariance kernel on real-world neonatal EEG for data imputation; and iii) the design of features for EEG based on MOSM hyperparameters and their validation for seizure detection (classification) in a patient specific approach.