학술논문

Attention to the Electroretinogram: Gated Multilayer Perceptron for ASD Classification
Document Type
Periodical
Source
IEEE Access Access, IEEE. 12:52352-52362 2024
Subject
Aerospace
Bioengineering
Communication, Networking and Broadcast Technologies
Components, Circuits, Devices and Systems
Computing and Processing
Engineered Materials, Dielectrics and Plasmas
Engineering Profession
Fields, Waves and Electromagnetics
General Topics for Engineers
Geoscience
Nuclear Engineering
Photonics and Electrooptics
Power, Energy and Industry Applications
Robotics and Control Systems
Signal Processing and Analysis
Transportation
Multilayer perceptrons
Logic gates
Transformers
Recording
Wavelet analysis
Retina
Social factors
Deep learning
Clinical diagnosis
ASD
deep learning
electroretinogram
ERG
gated MLP
transformer
waveform
Language
ISSN
2169-3536
Abstract
The electroretinogram (ERG) is a clinical test that records the retina’s electrical response to a brief flash of light as a waveform signal. Analysis of the ERG signal offers a promising non-invasive method for studying different neurodevelopmental and neurodegenerative disorders. Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by poor communication, reduced reciprocal social interaction, and restricted and repetitive stereotyped behaviors that should be detected as early as possible to ensure timely and appropriate intervention to support the individual and their family. In this study, we applied gated Multilayer Perceptron (gMLP) for the light-adapted ERG waveform classification as an effective alternative to Transformers. This study presents the first application of gMLP for ASD classification, which employs basic multilayer perceptrons with fewer parameters than Transformers. We compared the performance of different time-series models on an ASD-Control dataset and found that the superiority of gMLP in classification accuracy was the best at 89.7% compared to alternative models and supports the use of gMLP in classification models based on ERG recordings involving case-control comparisons.