학술논문

Volume Exploration Using Multidimensional Bhattacharyya Flow
Document Type
Periodical
Source
IEEE Transactions on Visualization and Computer Graphics IEEE Trans. Visual. Comput. Graphics Visualization and Computer Graphics, IEEE Transactions on. 29(3):1651-1663 Mar, 2023
Subject
Computing and Processing
Bioengineering
Signal Processing and Analysis
Active contours
Semantics
Tools
Three-dimensional displays
Histograms
Biomedical optical imaging
Optical feedback
Volume exploration
geometric active contours
Bhattacharyya flow
hierarchical decomposition
multi-GPU
Language
ISSN
1077-2626
1941-0506
2160-9306
Abstract
We present a novel approach for volume exploration that is versatile yet effective in isolating semantic structures in both noisy and clean data. Specifically, we describe a hierarchical active contours approach based on Bhattacharyya gradient flow which is easier to control, robust to noise, and can incorporate various types of statistical information to drive an edge-agnostic exploration process. To facilitate a time-bound user-driven volume exploration process that is applicable to a wide variety of data sources, we present an efficient multi-GPU implementation that (1) is approximately 400 times faster than a single thread CPU implementation, (2) allows hierarchical exploration of 2D and 3D images, (3) supports customization through multidimensional attribute spaces, and (4) is applicable to a variety of data sources and semantic structures. The exploration system follows a 2-step process. It first applies active contours to isolate semantically meaningful subsets of the volume. It then applies transfer functions to the isolated regions locally to produce clear and clutter-free visualizations. We show the effectiveness of our approach in isolating and visualizing structures-of-interest without needing any specialized segmentation methods on a variety of data sources, including 3D optical microscopy, multi-channel optical volumes, abdominal and chest CT, micro-CT, MRI, simulation, and synthetic data. We also gathered feedback from a medical trainee regarding the usefulness of our approach and discussion on potential applications in clinical workflows.