학술논문

Assessment of Acute Skin Irritation in Rabbits Using Electrical Impedance Model
Document Type
Conference
Source
2006 International Conference of the IEEE Engineering in Medicine and Biology Society Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE. :1665-1668 Aug, 2006
Subject
Bioengineering
Skin
Rabbits
Impedance
Biomedical engineering
Immune system
Electric resistance
Voltage
Epidermis
Frequency
Humans
Skin irritation
electrical impedance model
SLS
Language
ISSN
1557-170X
Abstract
This paper describes the use of an electrical impedance model to assess acute skin reactions to irritant over time. The applied method is noninvasive and quantitative and can detect the irritation before the visual signs. The results showed that the signs of acute irritation (oedema) were present until the second day after irritant application. The method is able to detect the initial phase of irritation and the assessment of regeneration time could be attained by a combination of more than one bioengineering methods.