학술논문

Lung Nodule Malignancy Prediction From Longitudinal CT Scans With Siamese Convolutional Attention Networks
Document Type
Periodical
Source
IEEE Open Journal of Engineering in Medicine and Biology IEEE Open J. Eng. Med. Biol. Engineering in Medicine and Biology, IEEE Open Journal of. 1:257-264 2020
Subject
Bioengineering
Components, Circuits, Devices and Systems
Computing and Processing
Cancer
Feature extraction
Computed tomography
Databases
Lung
Training
Biopsy
Lung cancer diagnosis
X-ray CT
longitudinal studies
siamese networks
deep learning
Language
ISSN
2644-1276
Abstract
Goal: We propose a convolutional attention-based network that allows for use of pre-trained 2-D convolutional feature extractors and is extendable to multi-time-point classification in a Siamese structure. Methods: Our proposed framework is evaluated for single- and multi-time-point classification to explore the value that temporal information, such as nodule growth, adds to malignancy prediction. Results: Our results show that the proposed method outperforms a comparable 3-D network with less than half the parameters on single-time-point classification and further achieves performance gains on multi-time-point classification. Conclusions: Attention-based, Siamese 2-D pre-trained CNNs lead to fast training times and are effective for malignancy prediction from single-time-point or multiple-time-point imaging data.