학술논문

Unifying Epidemic Models With Mixtures
Document Type
Periodical
Source
IEEE Transactions on Signal and Information Processing over Networks IEEE Trans. on Signal and Inf. Process. over Networks Signal and Information Processing over Networks, IEEE Transactions on. 10:239-252 2024
Subject
Signal Processing and Analysis
Computing and Processing
Communication, Networking and Broadcast Technologies
Predictive models
Data models
Biological system modeling
Pandemics
Mathematical models
COVID-19
Time series analysis
Complex networks
epidemics
forecasting
mixture models
Language
ISSN
2373-776X
2373-7778
Abstract
The COVID-19 pandemic has emphasized the need for a robust understanding of epidemic models. Current models of epidemics are classified as either mechanistic or non-mechanistic: mechanistic models make explicit assumptions on the dynamics of disease, whereas non-mechanistic models make assumptions on the form of observed time series. Here, we introduce a simple mixture-based model which bridges the two approaches while retaining benefits of both. The model represents time series of cases as a mixture of Gaussian curves, providing a flexible function class to learn from data, and we show that it arises as the natural outcome of a stochastic process based on a networked SIR framework. This allows learned parameters to take on a more meaningful interpretation compared to similar non-mechanistic models, and we validate the interpretations using auxiliary mobility data collected during the COVID-19 pandemic. We provide a simple learning algorithm to identify model parameters and establish theoretical results which show the model can be efficiently learned from data. Empirically, we find the model to have low prediction error. Moreover, this allows us to systematically understand the impacts of interventions on COVID-19, which is critical in developing data-driven solutions for controlling epidemics.