학술논문

PIXSCAN: pixel detector CT-scanner for small animal imaging
Document Type
Conference
Source
IEEE Nuclear Science Symposium Conference Record, 2005 Nuclear Science Symposium Nuclear Science Symposium Conference Record, 2005 IEEE. 4:2381-2385 2005
Subject
Nuclear Engineering
Power, Energy and Industry Applications
Fields, Waves and Electromagnetics
Engineered Materials, Dielectrics and Plasmas
Pixel
Animals
Positron emission tomography
Optical imaging
X-ray detection
X-ray detectors
Computed tomography
Biological tissues
Dynamic range
Radiation detectors
Language
ISSN
1082-3654
Abstract
The aims of the pixel detector CT-scanner for small animal imaging PIXSCAN are to provide high count rate and fast image readout, and to improve soft tissue contrast by energy discrimination, high dynamic range and low noise. As a proof of principle, the photon counting pixel detector built for X-ray synchrotron radiations was used to build a prototype demonstrator of the PIXSCAN device. This demonstrator was used to obtain first images of mice reconstructed by the FDK algorithm. A new photon counting chip with 130 /spl times/ 130 /spl mu/m/sup 2/ pixels (XPAD3) in sub-micron technology has been designed, results from simulations will be presented. We intend to combine XPAD3 detectors with positron emission tomography (PET) to study simultaneous PET/CT co-registration. A dedicated reconstruction algorithm is being developed for a special geometry combining a PET detector ring with a non-transaxial cone-beam X-ray CT design.