학술논문

Biocompatibility studies of materials used for chronically implantable microelectrodes
Document Type
Conference
Source
1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Microtechnologies in medicine and biology Microtechnologies in Medicine and Biology, 1st Annual International, Conference On. 2000. :521-525 2000
Subject
Components, Circuits, Devices and Systems
Bioengineering
Biological materials
Microelectrodes
Proteins
Electrodes
Biomedical materials
Probes
Glass
Implants
Indium tin oxide
Gold
Language
Abstract
The use of biocompatible materials is important in determining the longevity of chronically implantable microelectrodes. Protein adsorption is the initial event that takes place once an implant is in the body. These adsorbed proteins are then a significant influence on the subsequent adsorption of further proteins and cells; they thus dictate the interfacial reactions and ultimately the biocompatibility of the material. Results from protein adsorption studies on materials for sensing electrodes using ellipsometry are presented. The results suggest that among the materials investigated, indium tin oxide (ITO) is the best material in preventing protein adsorption, a characteristic required for electrode recording sites.