학술논문

Finite element modelling of extracellular potentials around thin-film microelectrode probes in invertebrate peripheral nerve
Document Type
Conference
Source
Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Engineering in medicine and biology Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE. 2:796-797 vol.2 1994
Subject
Bioengineering
Finite element methods
Extracellular
Probes
Substrates
Neurons
Conductivity
Microelectrodes
Mechanical engineering
Transistors
Transducers
Language
Abstract
Thin-film microelectrode probes (microprobes) are being investigated as peripheral nerve neural signal transducers for use in functional electrical stimulation orthoses. Finite element modelling techniques have been used to determine the effects of microprobe substrates on extracellular signals recorded intraneurally from locust peripheral nerve. The models show that probes with widths of the order of one-tenth the longitudinal extent of the action potential can have effects of amplifying signals from nerve fibres in front of the probe, and attenuating signals from fibres behind. The nerve sheath can also contribute to, and modulate, these effects.ETX