학술논문
Differentiation of Pulmonary Fibrosis by Means of Quantitative Lung Ultrasound Spectroscopy, First Clinical Study in Humans
Document Type
Conference
Source
2020 IEEE International Ultrasonics Symposium (IUS) Ultrasonics Symposium (IUS),2020 IEEE International. :1-4 Sep, 2020
Subject
Language
ISSN
1948-5727
Abstract
Lung ultrasound (LUS) imaging is nowadays recognized as a useful tool to extract clinical information on the state of the lung. Nevertheless, since LUS is mainly based on the interpretation of imaging artifacts, especially the B-line vertical artifacts, the derived diagnoses are subjective and qualitative. This work presents a quantitative method that aims at differentiating pulmonary fibrosis by means of a multifrequency analysis of B-lines performed with an LA533 (Esaote, Florence, Italy) linear array probe connected to the ULA-OP platform. Radio frequency (RF) data acquired from 20 patients and at different imaging frequencies (3, 4, 5, and 6 MHz) were stored, and the B-lines' frequency content (native frequency and bandwidth) was analyzed. The results show the potentiality to exploit the B-lines' frequency content for differentiating PF, in this cohort of patients, with a sensitivity and specificity equal to 100% and 90 %, respectively.