학술논문

3D imaging of microscopic structures using a proton beam
Document Type
Conference
Source
2003 IEEE Nuclear Science Symposium. Conference Record (IEEE Cat. No.03CH37515) Nuclear science symposium Nuclear Science Symposium Conference Record, 2003 IEEE. 3:1976-1978 Vol.3 2003
Subject
Nuclear Engineering
Power, Energy and Industry Applications
Fields, Waves and Electromagnetics
Engineered Materials, Dielectrics and Plasmas
Particle beams
Ion beams
Computed tomography
Probes
Collimators
Visualization
Optical microscopy
Energy loss
Helium
Imaging phantoms
Language
ISSN
1082-3654
Abstract
The use of ion beams a few micrometers in diameter as a tomographic probe could constitute a powerful tool for displaying the 3D structure of samples a few tens or hundreds of micrometers thick in a non-destructive way. At CENBG, ion beam micro-tomography has been developed for biomedical applications at the cell level. The combination of STIM and computed tomography gives access to the 3D distribution of density (in g/cm/sup 3/) within the analysed volume. The aim is to explore intracellular micro-structures, the sole preparation required being freeze-drying permitting analysis under vacuum.