학술논문

Tracking Cancer Cells with Microfluidic High Frequency DEP Cytometer Implemented on BiCMOS Lab-on-Chip Platform
Document Type
Conference
Source
2018 IEEE/MTT-S International Microwave Symposium - IMS Microwave Symposium - IMS, 2018 IEEE/MTT-S International. :104-107 Jun, 2018
Subject
Fields, Waves and Electromagnetics
Electrodes
Cancer
Electric fields
Dielectrophoresis
Cells (biology)
High Frequency Dielectrophoresis
Glioblastoma
BiCMOS Chip
Biological cell manipulation and analysis
Language
ISSN
2576-7216
Abstract
In this paper, a fully BiCMOS integrated microfluidic cell sorting platform for cell properties study is introduced. Operating in the radiofrequency range, the presented device combined Lab-on-Chip and IC technologies to achieve label free cytometry using in flow cell selective dielectrophoresis deviation. Taking benefit of CMOS stack and integration capability, the first prototypes demonstrate the ability to separate cells with different intracellular dielectric properties. These results pave the way to new innovative high throughput integrated IC solutions for detection of rare cells in the frame of cancer researches and treatment