학술논문

HRFlexToT: A High Dynamic Range ASIC for Time-of-Flight Positron Emission Tomography
Document Type
Periodical
Source
IEEE Transactions on Radiation and Plasma Medical Sciences IEEE Trans. Radiat. Plasma Med. Sci. Radiation and Plasma Medical Sciences, IEEE Transactions on. 6(1):51-67 Jan, 2022
Subject
Nuclear Engineering
Engineered Materials, Dielectrics and Plasmas
Bioengineering
Computing and Processing
Fields, Waves and Electromagnetics
Crystals
Energy resolution
Energy measurement
Timing
Scintillators
Power demand
Photonics
Fast front-end (FE) electronics
photo-detector technology
positron emission tomography
scintillator
silicon photomultipliers (SiPM)
time-of-flight positron emission tomography (TOF-PET)
Language
ISSN
2469-7311
2469-7303
Abstract
Time-of-Flight positron emission tomography scanners demand fast and efficient photo sensors and scintillators coupled to fast readout electronics. This article presents the high resolution flexible Time-over-Threshold (HRFlexToT), a 16-channel application-specific-integrated circuit for silicon photomultipliers (SiPM) anode readout manufactured using XFAB 0.18- $\mu \text{m}$ CMOS technology. The main features of the HRFlexToT are a linear Time-over-Threshold with an extended dynamic range (10 bits) for energy measurement, low power consumption (≈ 3.5 mW/ch), and an excellent timing response. The experimental measurements show an energy linearity error of ≈ 3% and an energy resolution of about 12% at 511 keV. Single-photon time resolution measurements performed using an Fondazione Bruno Kessler (FBK) SiPM NUV-HD ( $4 \times 4$ mm 2 pixel, 40- $\mu \text{m}$ cell) and a Hamamatsu SiPM S13360-3050CS are around 142 and 167 ps full width at half maximum (FWHM), respectively. Coincidence time resolution (CTR) measurements with small cross-section pixelated crystals (LSO:Ce,Ca 0.4%, $2 \times 2 \times 5$ mm 3 ) coupled to the same Hamamatsu S13360-3050CS and FBK NUV-HD sensors yield a CTR of 117 ps and 119 ps, respectively. Measurements performed with a large cross-section monolithic crystal (LFS crystal measuring $25 \times 25 \times 20$ mm 3 ) and a Hamamatsu SiPM array S13361-6050NE-04 show a CTR of 324 ps FWHM after time-walk and time-skew correction.