부산대학교 도서관

Currently, the default brain mode known in the scientific literature uses hemodynamic or electrical data to assess the activity and connection of different brain structures in the basal state. But these data are measured at random times of the day. Conversely, research has shown that every structure in the human body has its own physiological dynamics throughout the day. We therefore designed and carried out a study to assess, this time on the basis of metabolic data, the diurnal brain dynamics in nine different brain structures. The aim was also to establish an initial overview of the brain's metabolic connections. Our results are encouraging and in line with the scientific literature. We were able to identify the diurnal metabolic dynamics, as a function of circadian rhythm, of the nine brain zones in the basal state, as well as certain correlations between them. Furthermore, we observed that in two correlated zones, metabolites follow the same dynamics but not in the same quantities. Finally, the diurnal metabolic dynamics of lactate are surprising. None of the nine zones correlate with each other. In addition, in the same brain structure, its diurnal metabolic dynamics are also independent of other metabolites.