학술논문

Optimized Sensor for Broadband Dielectrometry of Biological Liquids of Small Volume
Document Type
Conference
Source
2021 51st European Microwave Conference (EuMC) European Microwave Conference (EuMC), 2021 51st. :781-784 Apr, 2022
Subject
Components, Circuits, Devices and Systems
Fields, Waves and Electromagnetics
Temperature measurement
Liquids
Permittivity measurement
Volume measurement
Biomedical measurement
Transmission line measurements
Biology
Microwave dielectric spectroscopy
sensor
permittivity
biological liquid
Language
Abstract
In this article, the results of a tailored calibration scheme applied to a transmission line sensor for measuring the relative permittivity of biological liquids in a broad microwave frequency range are discussed. The microwave sensor design enables measurements of relative permittivity values of biological samples with a small volume of only 70nl. The relative permittiv-ity is extracted for aqueous solutions of Sodium Chloride (NaCl) and Bovine Serum Albumin (BSA) over a broadband range from 10 MHz to 40 GHz at a constant temperature of 21.5 ±0.4° C. The measured permittivity of NaCI solution matches closely with simulated and literature data with relative error of $\Delta\varepsilon_{r}=0.51\%$ at 20 GHz. Further, the broadband relative permittivity results are compared to extracted permittivity values obtained from a resonant measurement method based on a quartz whispering gallery mode resonator at discrete frequencies between 30 GHz and 40 GHz.