학술논문

In Silico Study of the Surface Plasmon Resonance Use for Detecting Cancer in the Colorectal Mucosa
Document Type
Conference
Source
2022 IEEE International Instrumentation and Measurement Technology Conference (I2MTC) Instrumentation and Measurement Technology Conference (I2MTC), 2022 IEEE International. :1-6 May, 2022
Subject
Bioengineering
Engineering Profession
General Topics for Engineers
Signal Processing and Analysis
Reflectivity
Silver
Gold
Pathology
Sensitivity
Thick films
Mathematical models
colorectal cancer
SPR sensor
trapezoidal prism
thin metal film
Language
ISSN
2642-2077
Abstract
This paper presents an in silico study regarding the use of a trapezoidal prism-based surface plasmon resonance sensor to detect cancer in the colorectal mucosa. The parameters of the surface plasmon resonance curves o the multilayered structure operating in the wavelength interrogation mode were studied by exploring the metallic film characteristics. The height of the thin films of gold, silver, and copper was studied to find the best sensitivity. Whereas a p-polarized light beam, with a range of 450 to 820 nm, falls on the multilayered structure at an angle of 68 degrees, the Fresnel equations were chosen to calculate the reflectance curve. From the evaluated results, we realized that the greater results were reached when we used a 40 nm silver film, resulting in 6,454.12 nm/RIU for a sensitivity value.