학술논문

Evaluation of Methods to Characterize the Change of the Respiratory Sinus Arrhythmia with Age in Sleep Apnea Patients
Document Type
Conference
Source
2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) Engineering in Medicine and Biology Society (EMBC), 2019 41st Annual International Conference of the IEEE. :1588-1591 Jul, 2019
Subject
Bioengineering
Heart rate variability
Sleep apnea
Estimation
Time-frequency analysis
Entropy
Bandwidth
Language
ISSN
1558-4615
Abstract
The High Frequency (HF) band of the power spectrum of the Heart Rate Variability (HRV) is widely accepted to contain information related to the respiration. However, it is known that this often results in misleading estimations of the strength of the Respiratory Sinus Arrhythmia (RSA). In this paper, different approaches to characterize the change of the RSA with age, combining HRV and respiratory signals, are studied. These approaches are the bandwidths in the power spectral density estimations, bivariate phase rectified signal averaging, information dynamics, a time-frequency representation, and a heart rate decomposition based on subspace projections. They were applied to a dataset of sleep apnea patients, specifically to periods without apneas and during NREM sleep. Each estimate reflected a different relationship between RSA and age, suggesting that they all capture the cardiorespiratory information in a different way. The comparison of the estimates indicates that the approaches based on the extraction of respiratory information from HRV provide a better characterization of the age-dependent degradation of the RSA.