학술논문

Design and experimental study of electrochemical detector with EWOD for chemical analysis
Document Type
Conference
Source
The 5th 2012 Biomedical Engineering International Conference Biomedical Engineering International Conference (BMEiCON), 2012. :1-5 Dec, 2012
Subject
Bioengineering
Communication, Networking and Broadcast Technologies
Components, Circuits, Devices and Systems
Computing and Processing
Signal Processing and Analysis
Electrodes
Microcontrollers
Detectors
Microfluidics
Merging
Gold
Electrowetting on Dielectric (EWOD)
Electrochemical detector
Digital Microfluidics
Language
Abstract
In this work, we describe design and experimental studies of a electrochemical detector by using electrowetting on dielectric (EWOD) digital microfluidics microchip for chemical analysis. For the design, the electrochemical EWOD digital microfluidics system consists of T-junction EWOD microchip for merging buffer reagent and analyte droplets and three internal electrochemical detector at the end of T-junction. Three electrodes consist of Au working, Au reference, and Au auxiliary for rapid chemical analysis with minimal reagent consumption. In experiment, the single-plate EWOD microchip has been successfully fabricated and tested to study possibility of moving (merging and transporting) droplet on the microchip. For controlling droplet, we designed electrical circuits using a microcontroller to control relays that switching applied voltage to control electrodes on and off. Interfacing RS232 with microcontroller makes the droplet merging. Merging a droplet can be modified from personal computer by sending commands from a PC to a microcontroller. The tested results show that successfully move (merging) of deionized droplets along patterned single plate EWOD device by controlling of microcontroller.