학술논문

Accessing cortical tonotopic organization by microstimulation of cochlear nucleus
Document Type
Conference
Source
First International IEEE EMBS Conference on Neural Engineering, 2003. Conference Proceedings. Neural engineering Neural Engineering, 2003. Conference Proceedings. First International IEEE EMBS Conference on. :161-164 2003
Subject
Computing and Processing
Components, Circuits, Devices and Systems
Signal Processing and Analysis
Microelectrodes
Electrodes
Brainstem implants
Deafness
Polyimides
Neck
Surgery
Acoustic devices
Prosthetics
Rats
Language
Abstract
Auditory brainstem implant (ABI) that electrically stimulates the cochlear nucleus has been clinically used for rehabilitation of deaf patients with bilateral acoustic neuromas. A current prosthetic device, however, cannot evoke even pitch sensation and thus brings few benefits. The present work purposes to verify ABI capability by physiological experiments using rats. Our experimental system includes a spike microelectrode array for cochlear nucleus microstimulation and a surface microelectrode array for mapping evoked-potentials over the auditory cortex. We compare pure-tone-evoked cortical potential patterns with those evoked by cochlear nucleus microstimulation. Our experimental results strongly suggest the microstimulation on the dorsal and ventral nuclei can access the cortical tonotopic organization, as acoustic stimuli do, possibly indicating the stimulation can evoke pitch sensation and thus substantially promising ABI capability.