학술논문

Probabilistic Inference of Comorbidities from Symptoms in Patients with Atrial Fibrillation: An Ontology-Driven Hybrid Clinical Decision Support System
Document Type
Conference
Source
2022 Computing in Cardiology (CinC) Computing in Cardiology (CinC), 2022. 498:1-4 Sep, 2022
Subject
Bioengineering
Computing and Processing
Signal Processing and Analysis
Decision support systems
Arrhythmia
Knowledge based systems
Atrial fibrillation
Probabilistic logic
Complexity theory
Cardiology
Language
ISSN
2325-887X
Abstract
Atrial fibrillation $(AF)$ is the most prevalent cardiac arrhythmia. While $AF$ is a cardiological disease, its risk factors and mechanisms are often rooted in non-cardiological comorbidities, introducing complexity in the treatment of the heterogeneous patient population. This study presents the development of a clinical decision support system (CDSS), which aims to mitigate potential challenges of the cross-disciplinarity of $AF$ A knowledge base is implemented to capture the hierarchical nature of relevant concepts. $Nai\dot{v}e$ Bayes classifiers are used to predict the patient comorbidities related to $AF$ mechanisms and risk factors based on provided symptoms. The resulting CDSS infers comorbidities with a top-k accuracy of 0.53, 0.80, and 0.88 for $k=1, 3$, and 5 respectively.