학술논문

Efficient Malaria Parasite Detection From Diverse Images of Thick Blood Smears for Cross-Regional Model Accuracy
Document Type
Periodical
Source
IEEE Open Journal of Engineering in Medicine and Biology IEEE Open J. Eng. Med. Biol. Engineering in Medicine and Biology, IEEE Open Journal of. 4:226-233 2023
Subject
Bioengineering
Components, Circuits, Devices and Systems
Computing and Processing
Malaria
Microscopy
Blood
Image segmentation
Smart phones
Africa
Medical diagnostic imaging
Computer aided diagnosis
Parasitic diseases
Neural networks
Computer-aided diagnosis
image segmentation
malaria parasites
microscope
neural networks
smartphones
Language
ISSN
2644-1276
Abstract
Goal : The purpose of this work is to improve malaria diagnosis efficiency by integrating smartphones with microscopes. This integration involves image acquisition and algorithmic detection of malaria parasites in various thick blood smear (TBS) datasets sourced from different global regions, including low-quality images from Sub-Saharan Africa. Methods: This approach combines image segmentation and a convolutional neural network (CNN) to distinguish between white blood cells, artifacts, and malaria parasites. A portable system integrates a microscope with a graphical user interface to facilitate rapid malaria detection from smartphone images. We trained the CNN model using open-source data from the Chittagong Medical College Hospital, Bangladesh. Results: The validation process, using microscopic TBS from both the training dataset and an additional dataset from Sub-Saharan Africa, demonstrated that the proposed model achieved an accuracy of 97.74% ± 0.05% and an F1-score of 97.75% ± 0.04%. Remarkably, our proposed model with AlexNet surpasses the reported literature performance of 96.32%. Conclusions: This algorithm shows promise in aiding malaria-stricken regions, especially those with limited resources.