학술논문

The Effects of Compton Camera Data Acquisition and Readout Timing on PG Imaging for Proton Range Verification
Document Type
Periodical
Source
IEEE Transactions on Radiation and Plasma Medical Sciences IEEE Trans. Radiat. Plasma Med. Sci. Radiation and Plasma Medical Sciences, IEEE Transactions on. 6(3):366-373 Mar, 2022
Subject
Nuclear Engineering
Engineered Materials, Dielectrics and Plasmas
Bioengineering
Computing and Processing
Fields, Waves and Electromagnetics
Protons
Particle beams
Crystals
Data acquisition
Data models
Timing
Imaging
Compton camera (CC)
prompt gamma (PG) imaging
proton range verification
proton therapy
Language
ISSN
2469-7311
2469-7303
Abstract
The purpose of this article was to determine how the characteristics of the data acquisition (DAQ) electronics of a Compton camera (CC) affect the quality of the recorded prompt gamma (PG) interaction data and the reconstructed images, during clinical proton beam delivery. We used the Monte-Carlo-plus-detector-effect (MCDE) model to simulate the delivery of a 150-MeV clinical proton pencil beam to a tissue-equivalent plastic phantom. With the MCDE model, we analyzed how the recorded PG interaction data changed as two characteristics of the DAQ electronics of a CC were changed: 1) the number of data readout channels and 2) the active charge collection, readout, and reset time. As the proton beam dose rate increased, the number of recorded PG single-, double-, and triple-scatter events decreased by a factor of $60\times $ for the current DAQ configuration of the CC. However, as the DAQ readout channels were increased and the readout/reset timing decreased, the number of recorded events decreased by $< 5\times $ at the highest clinical dose rate. The increased number of readout channels and reduced readout/reset timing also resulted in higher quality recorded data. That is, a higher percentage of the recorded double- and triple-scatters were “true” events (caused by a single incident gamma) and not “false” events (caused by multiple incident gammas). The increase in the number and the quality of recorded data allowed higher quality PG images to be reconstructed even at the highest clinical dose rates.