학술논문
Radiosensitization in Cancer Treatment with Gold nanoparticles through Synergistic Sonoporation
Document Type
Conference
Author
Source
2019 IEEE International Ultrasonics Symposium (IUS) Ultrasonics Symposium (IUS), 2019 IEEE International. :1536-1538 Oct, 2019
Subject
Language
ISSN
1948-5727
Abstract
We demonstrated synergistic radiosensitization in human liver cancer using gold nanoparticle-encapsulated microbubbles (AuMB) and ultrasound. Microbubbles-mediated sonoporation enhanced cellular uptake of gold nanoparticles (AuNP). Higher cavitation signals were associated with more DNA damages and inferior cancer cell survivals after mega-voltage (MV) X-ray irradiation.