학술논문

Integrated Clustering of Cancer Genes Based on Local Weighting
Document Type
Conference
Source
2023 3rd International Symposium on Computer Technology and Information Science (ISCTIS) Computer Technology and Information Science (ISCTIS), 2023 3rd International Symposium on. :812-818 Jul, 2023
Subject
Communication, Networking and Broadcast Technologies
Computing and Processing
Signal Processing and Analysis
Weight measurement
Information science
Uncertainty
Clustering methods
Entropy
Bipartite graph
Reliability
Component clustering
Ensemble clustering
Local weighting
Cancer genes
Language
Abstract
This paper proposes propose a novel ensemble clustering method to address the problem that integrated clustering typically treats all component clusters equally without considering their reliability, thereby being vulnerable to low-quality component clusters. Firstly, five clustering methods are adopted to generate different component clusters. Secondly, a new ensemble-driven clustering index (ECI) based on the unreliability of component clusters is introduced to construct a pool of candidate component clusters and discard low-quality ones. To capture the local diversity of the ensemble, we utilize a matrix known as a locally weighted co-association matrix (LWCA), and a new consistency function, improved locally weighted graph partitioning with consistency consideration (RLWGP), we propose a further approach by incorporating cluster labels across the ensemble through an entropy criterion. In this approach, we consider both clusters and objects as nodes in the graph, and the advantage of bipartite graph structure facilitates efficient graph partitioning and preferable clustering performance. Our experimental results, conducted on various cancer datasets, demonstrate that the proposed method outperforms existing methods in terms of accuracy, precision, and recall.