학술논문

Fetal MRI by Robust Deep Generative Prior Reconstruction and Diffeomorphic Registration
Document Type
Periodical
Source
IEEE Transactions on Medical Imaging IEEE Trans. Med. Imaging Medical Imaging, IEEE Transactions on. 42(3):810-822 Mar, 2023
Subject
Bioengineering
Computing and Processing
Image reconstruction
Strain
Magnetic resonance imaging
Estimation
Brain modeling
Reconstruction algorithms
Extraterrestrial measurements
Fetal magnetic resonance imaging
slice to volume reconstruction
generative image priors
diffeomorphic image registration
gestational age prediction
Language
ISSN
0278-0062
1558-254X
Abstract
Magnetic resonance imaging of whole fetal body and placenta is limited by different sources of motion affecting the womb. Usual scanning techniques employ single-shot multi-slice sequences where anatomical information in different slices may be subject to different deformations, contrast variations or artifacts. Volumetric reconstruction formulations have been proposed to correct for these factors, but they must accommodate a non-homogeneous and non-isotropic sampling, so regularization becomes necessary. Thus, in this paper we propose a deep generative prior for robust volumetric reconstructions integrated with a diffeomorphic volume to slice registration method. Experiments are performed to validate our contributions and compare with ifdefined tmiformat R2.5a state of the art method methods in the literature in a cohort of 72 fetal datasets in the range of 20-36 weeks gestational age. Results suggest improved image resolution Quantitative as well as radiological assessment suggest improved image quality and more accurate prediction of gestational age at scan is obtained when comparing to a state of the art reconstruction method methods. In addition, gestational age prediction results from our volumetric reconstructions compare favourably are competitive with existing brain-based approaches, with boosted accuracy when integrating information of organs other than the brain. Namely, a mean absolute error of ${0}.{618}$ weeks ( ${R}^{{2}}={0}.{958}$ ) is achieved when combining fetal brain and trunk information.