학술논문

Multifunctional system for observing, measuring and analyzing stimulation-evoked neurochemical signaling
Document Type
Conference
Source
2017 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Medical Measurements and Applications (MeMeA), 2017 IEEE International Symposium on. :349-354 May, 2017
Subject
Engineering Profession
Power capacitors
Switches
Semiconductor device measurement
Impedance
Electric variables measurement
Modulation
Wireless sensor networks
voltammetry
stimulation
neurotransmitter
neuro-modulation
Language
Abstract
The ability to measure neurotransmitter activity using implanted electrochemical sensors offers researchers a potent technique for analyzing neural activity across specific neural circuitry. We have developed a wirelessly controlled device, WINCS Harmoni, to observe and measure neurotransmitter dynamics at up to four separate sensors, with high temporal and spatial resolution. WINCS Harmoni also incorporates a versatile neurostimulator that can be synchronized with electrochemical recording. The WINCS Harmoni platform is thus optimally suited for probing the neurochemical effects of neurostimulation, and may in turn enable the development of personalized therapies for multiple brain disorders.