학술논문
Nonlinear analysis of failed ventricular defibrillation
Document Type
Conference
Source
Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439) Engineering in medicine and biology society Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE. 1:196-199 Vol.1 2003
Subject
Language
ISSN
1094-687X
Abstract
A high-speed video camera and voltage-sensitive dyes were used to acquire high resolution (80 /spl times/ 80 pixels) and high-speed (1 ms/frame) optical signals of ventricular fibrillation in a Langendorff-perfused porcine heart. The resulting spatiotemporal dynamics were recorded before and after the application of a defibrillation shock in order to study the mechanism of defibrillation failure. We created time space cubes and calculated nonlinear synchronization index measures to qualify the evolution of different types of activity on the heart surface (focal, reentry). We observed changes with time in all types of analysis, thus establishing these techniques as viable methods for detecting defibrillation failure before reentry reestablishes itself.