학술논문

A 97-Channel Read-Out ASIC for an Electrophysiological Mapping Catheter With an Optical Link
Document Type
Periodical
Source
IEEE Transactions on Biomedical Circuits and Systems IEEE Trans. Biomed. Circuits Syst. Biomedical Circuits and Systems, IEEE Transactions on. 18(1):76-88 Feb, 2024
Subject
Bioengineering
Components, Circuits, Devices and Systems
Catheters
Optical fiber communication
Light emitting diodes
Biomedical optical imaging
Application specific integrated circuits
Atrial fibrillation
System-on-chip
basket catheter
blue LED
EP
mapping catheter
MRI
multi-channel read-out ASIC
optical link
system-on-chip (SoC)
Language
ISSN
1932-4545
1940-9990
Abstract
Electrophysiological (EP) mapping catheters are medical equipment, which are widely used to diagnose and treat atrial fibrillation. The electrophysiology signals are sensed by the catheter's electrodes, for which a large electrode count becomes more and more essential because of the demand for a higher local resolution. A drawback of the large electrode count is the effort to pass through and to integrate the wires inside the catheter shaft. To overcome with this issue, this article describes the realization of an EP ASIC, which is placed close to the 97 electrodes and to perform an in-tip digitization. Thanks to an integrated optical link, only a single fiber is required to connect the catheter tip to an externally located electro-optical unit and thus shrinking the shaft volume to a minimum. The fiber is used to guide light from the electro-optical unit to the catheter tip and illuminate a blue LED, which is located close to the EP ASIC and acts as a photovoltaic cell. The EP ASIC is designed to use the LED as power source and a data transceiver while performing signal conditioning and digitization of the EP signals at the same time. The EP signals are captured with the ASIC's multi-channel read-out circuit consisting of 97 fully differential preamplifiers and additional filter stages. A switch network sequentially selects one single channel for further amplification and digitization of the EP signal. The read-out circuit is designed to process signals in the range of 500 μVpp to 20 mVpp with a bandwidth of 5 Hz to 100 Hz.