학술논문

Anisotropic equivalent conductivity tensors for bioelectric modeling of partial volume effects in cerebrospinal fluid spaces
Document Type
Conference
Source
2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro Biomedical Imaging: From Nano to Macro, 2011 IEEE International Symposium on. :1109-1112 Mar, 2011
Subject
Bioengineering
Communication, Networking and Broadcast Technologies
Computing and Processing
Signal Processing and Analysis
Robotics and Control Systems
Brain modeling
Conductivity
Solid modeling
Computational modeling
Tensile stress
Biological system modeling
Head
Language
ISSN
1945-7928
1945-8452
Abstract
Accurate modeling of bioelectric propagation within the head is necessary for precise electromagnetic source localization. We present here a new approach for modeling spaces fractionally composed of grey matter and cerebrospinal fluid. Using information about the orientation of the cortical surface, we construct anisotropic conductivity tensors to model the partial volume effects frequently present within sulci. Our results indicate that the CSF region has significant effect upon the resulting model, and can more accurately be accounted for using anisotropic conductivities. We validate our method using a whole brain statistical error analysis of the signal topography and magnitude.