학술논문

Integrated Robotic System for the Development Lateral Flow Assays
Document Type
Conference
Source
2019 IEEE Global Humanitarian Technology Conference (GHTC) Global Humanitarian Technology Conference (GHTC), 2019 IEEE. :1-4 Oct, 2019
Subject
Communication, Networking and Broadcast Technologies
Engineering Profession
General Topics for Engineers
Power, Energy and Industry Applications
Transportation
Robots
Strips
Diseases
Liquids
Immune system
Plasmas
Optimization
automation
factorial
response surface
Language
Abstract
Lateral flow assays (LFAs) are the most widely used diagnostic tools in resource-limited settings. To make the development and optimization of LFAs more efficient, we developed an integrated system that comprises design of experiment software and robotic liquid handling hardware. We verified the performance of this system in comparison with a human operator and demonstrated its use in experiments during the development of a malaria antigen assay, varying both discrete and continuous variables. These results highlight the utility of this system for the efficient and rapid development of LFAs and other assays.