학술논문

Orbital Lymphoproliferative Disorder Diagnosis with Incomplete Multimodal Images based on Self-/Cross-Representation and Hypergraph Ensemble
Document Type
Conference
Source
2023 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Bioinformatics and Biomedicine (BIBM), 2023 IEEE International Conference on. :1575-1581 Dec, 2023
Subject
Bioengineering
Computing and Processing
Engineering Profession
Robotics and Control Systems
Signal Processing and Analysis
Correlation
Fuses
Semantics
Imaging
Feature extraction
Orbits
Distance measurement
Orbital Lymphoproliferative Disorder
Incomplete Multimodality
Self-/cross-representation
Hypergraph
Ensemble
Language
ISSN
2156-1133
Abstract
Orbital lymphoproliferative disorders (OLPDs) are complex orbital mass-like lesions ranging from benign to malignant. Precise preoperative diagnosis of OLPDs holds profound importance in facilitating timely and effective patient management. Recent studies have shown that exploiting multimodal images can boost the performance in identifying different orbital lesions. However, one or several imaging modalities are sometimes missing in practical applications, which has not yet been properly addressed in existing studies. To this end, we propose a novel OLPD diagnostic method with incomplete multimodal images based on self-/cross-representation and hypergraph ensemble. Specifically, in the first stage, we develop a self-representation network to extract unimodal features and a cross-representation network to impute missing features. In the second stage, by using unimodal features as input, we construct a hypergraph for each modality to make unimodal diagnosis; while for multimodal diagnosis we conduct a multi-view grouping fusion method to reduce the semantic gap between multimodal features and fuse multiple unimodal hypergraphs as multimodal hypergraph to perform multimodal diagnosis. In the third stage, we propose an ensemble strategy that incorporates unimodal diagnosis and multimodal diagnosis to accomplish the final decision. Extensive experiments demonstrate that the proposed model outperforms the state-of-the-art approaches.