학술논문

Robustness of Deep Learning Methods for Ocular Fundus Segmentation: Evaluation of Blur Sensitivity
Document Type
Conference
Source
2020 International Conference on INnovations in Intelligent SysTems and Applications (INISTA) INnovations in Intelligent SysTems and Applications (INISTA), 2020 International Conference on. :1-7 Aug, 2020
Subject
Bioengineering
Communication, Networking and Broadcast Technologies
General Topics for Engineers
Robotics and Control Systems
Signal Processing and Analysis
Image segmentation
Robustness
Testing
Neural networks
Retina
Machine learning
Sensitivity
Retinal vessel segmentation
blurry retinal image
neural network robustness
convolutional neural networks
deep learning
Language
Abstract
This paper analyzes the sensitivity of deep learning methods for ocular fundus segmentation. We use an empirical methodology based on non-adversarial perturbed datasets. The research is motivated by the perceived needs of mass screening and self-administered tests in which autonomous or semi-autonomous artificially intelligent methods are needed and may be given substandard images with focus issues. These substandard pictures are simulated using blurring algorithms of varying designs and kernel sizes which are subjected to a test of inter-network sensitivity. The network's result on an unblurred original is derived from the testing subset of the DRIVE ocular fundus image dataset used as the ground truth. The networks studied were VesselUNet (Ronnenberger et al. and Huang et al.), VesselGAN (Son et al.), and VesselFCNN (Oliveira et al.). Statistical analysis of the resultant n = 3600 sample has determined that the datapoints indicating sensitivity over kernel size can be fitted with a sigmoid (with a maximum final tolerance of 9.33e-6), and that it can be shown, using robust pairwise Holm-corrected comparisons, that VesselUNet is the least sensitive (with p-values