학술논문
Ant colony optimisation of decision trees for the detection of gene-gene interactions
Document Type
Conference
Author
Source
2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Bioinformatics and Biomedicine (BIBM), 2014 IEEE International Conference on. :57-61 Nov, 2014
Subject
Language
Abstract
In this paper ant colony optimisation is used to derive near-optimal interactions between a number of single nucleotide polymorphisms. This approach is used to discover small numbers of single nucleotide polymorphisms that are combined into a decision tree or contingency table model. It is shown that these two models can be highly discriminatory from a statistical perspective and a number of the single nucleotide polymorphisms discovered have been identified previously in large genome-wide association studies.