학술논문

Automatic dendrite spines detection from x-ray tomography volumes
Document Type
Conference
Source
2013 IEEE 10th International Symposium on Biomedical Imaging Biomedical Imaging (ISBI), 2013 IEEE 10th International Symposium on. :436-439 Apr, 2013
Subject
Bioengineering
Components, Circuits, Devices and Systems
Computing and Processing
Signal Processing and Analysis
Transforms
Noise
Image reconstruction
Neurons
Scanning electron microscopy
Dendritic spine
X-Ray micro-tomography
3D Hough transform
Point Process
Language
ISSN
1945-7928
1945-8452
Abstract
We consider the problem of dendritic spine detection from X-ray micro-tomographic volumes that allow huge volume of tissue visualization. To compensate for the noise in data that induces false positives in the spine detection process, we first segment the dendrites. This segmentation is obtained by computing the medial axis and approximating the results by segments obtained with a 3D Hough transform. Dendrites are then reconstructed and a spine mask is obtained using the typical diameter of dendrites and distance between spine and dendrites. A point process is then optimized on this mask, thus providing the spine detection.