학술논문

Standards study for quantitative analysis of trace elements in biological tissue using secondary ion mass spectrometry
Document Type
Conference
Source
1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Engineering in Medicine and Biology Society, 1992 14th Annual International Conference of the IEEE. 1:88-90 Oct, 1992
Subject
Bioengineering
Communication, Networking and Broadcast Technologies
Components, Circuits, Devices and Systems
Computing and Processing
Signal Processing and Analysis
Robotics and Control Systems
Artificial intelligence
Biology
Ions
Spectroscopy
Pathology
Language
Abstract
Trials have been carried out to establish appropriate standards for quantitative biological microanalysis using SIMS. This feasibility study has demonstrated that gelatin and ion exchange resin microbeads embedded in epoxy resin could be homogenously loaded with Al in a large range of concentrations (up to 2000 ppm). We have obtained good linear correlations between trace element / internal reference element ratio and trace element concentrations verified by chemical analysis techniques. Furthermore, it has been possible to determine unknown concentrations with precision within one standard deviation of the chemically determined concentrations.