학술논문

Detector design for range monitoring in hadron therapy by means of image reconstruction
Document Type
Conference
Source
2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC) Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2012 IEEE. :3887-3889 Oct, 2012
Subject
Bioengineering
Signal Processing and Analysis
Communication, Networking and Broadcast Technologies
Components, Circuits, Devices and Systems
Computing and Processing
Hadron-therapy
prompt gamma
slit collimator
reconstruction
Language
ISSN
1082-3654
Abstract
Hadron therapy offers some advantages over conventional therapy. However, small errors in particle range may significantly increase dose delivered to healthy tissue or produce incomplete coverage of the target volume. Consequently, developing a method to verify the delivered dose and the Bragg peak location during treatment is crucial. Recent investigations have shown that the prompt gamma photons produced during the patient irradiation with hadron beams are in good correlation with the dose delivered to the patient and therefore, they can be used for in-beam range monitoring. Slit collimated gamma camera has been proposed as a system for prompt gamma imaging. Image reconstruction can potentially improve the accuracy of that system. The purpose of this work is to study and implement a reconstruction process for in-beam range monitoring using slit-collimated gamma camera. Obtained results will guide the design of the slit-collimated camera. The results indicate that the range monitoring is possible with slit camera using ML-EM reconstruction. The average deviation obtained using reconstructed profiles is 2.06 mm.