학술논문
A software package for next-gen bisulfite sequencing data analysis
Document Type
Conference
Source
2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW) Bioinformatics and Biomedicine Workshops (BIBMW), 2011 IEEE International Conference on. :1061-1062 Nov, 2011
Subject
Language
Abstract
Bisulfite sequencing (BS-seq) is one of the most important sequencing protocols for genome-wide DNA methylation studies. However, it causes significant challenges in computation because it converts unmethylated cytosines to thymines. This paper presents a software package to address those challenges and to provide various kinds of analysis modules, from mapping to comparing multiple samples.