학술논문

Analysis and Visualization of Mutation Enrichments for Selected Genomic Regions and Cancer Types
Document Type
Conference
Source
2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Bioinformatics and Biomedicine (BIBM), 2019 IEEE International Conference on. :652-655 Nov, 2019
Subject
Bioengineering
Computing and Processing
Mutation analysis
Data exploration and visualization
Statistical testing
User-friendly tools
Language
Abstract
Several studies highlight the relevance of somatic mutations in non-coding regions of the genome which exhibit common interesting behaviors. MutViz is a tool for the identification of mutation enrichments on arbitrary sets of user-defined regions; for a variety of cancer types, it contains preloaded mutations from public datasets, well organized within an effective database organization. MutViz provides a user-friendly interface helping the user in providing sets of regions as input and in obtaining their fast exploration as output, together with simple statistical testing of novel hypotheses.