학술논문

Full Characterization of in vivo Muscle as an Elastic, Incompressible, Transversely Isotropic Material Using Ultrasonic Rotational 3D Shear Wave Elasticity Imaging
Document Type
Periodical
Source
IEEE Transactions on Medical Imaging IEEE Trans. Med. Imaging Medical Imaging, IEEE Transactions on. 41(1):133-144 Jan, 2022
Subject
Bioengineering
Computing and Processing
Muscles
Transducers
Imaging
Three-dimensional displays
Propagation
Anisotropic magnetoresistance
Ultrasonic imaging
Muscle
shear wave elastography
transverse isotropy
Language
ISSN
0278-0062
1558-254X
Abstract
Using a 3D rotational shear wave elasticity imaging (SWEI) setup, 3D shear wave data were acquired in the vastus lateralis of a healthy volunteer. The innate tilt between the transducer face and the muscle fibers results in the excitation of multiple shear wave modes, allowing for more complete characterization of muscle as an elastic, incompressible, transversely isotropic (ITI) material. The ability to measure both the shear vertical (SV) and shear horizontal (SH) wave speed allows for measurement of three independent parameters needed for full ITI material characterization: the longitudinal shear modulus ${\mu }_{L}$ , the transverse shear modulus ${\mu }_{T}$ , and the tensile anisotropy ${\chi }_{E}$ . Herein we develop and validate methodology to estimate these parameters and measure them in vivo , with ${\mu }_{L} = 5.77\pm 1.00$ kPa, ${\mu }_{T} = 1.93\pm 0.41$ kPa (giving shear anisotropy ${\chi _\mu } = 2.11\pm 0.92$ ), and ${\chi }_{E} = 4.67\pm 1.40$ in a relaxed vastus lateralis muscle. We also demonstrate that 3D SWEI can be used to more accurately characterize muscle mechanical properties as compared to 2D SWEI.