학술논문
A silicon microelectrode array for simultaneous recording and stimulation in the brain of behaving animals
Document Type
Conference
Author
Source
Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439) Engineering in medicine and biology society Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE. 2:1968-1971 Vol.2 2003
Subject
Language
ISSN
1094-687X
Abstract
This paper presents an eight-channel silicon neural probe with integrated CMOS circuitry designed for simultaneous recording and stimulation in the brain. The probe includes eight on-chip amplifiers that can be individually bypassed, allowing direct access to the indium sites for electrical stimulation. The on-probe amplifiers have a gain of 38.9dB, an upper cutoff frequency of 9.9 kHz, and an input referred noise of 9.2 /spl mu/Vrms from 100 Hz to 10 kHz. The low-frequency cutoff of the amplifier is tunable to allow the recording of field potentials and minimize stimulus artifact. The on-probe circuitry consumes 672 /spl mu/W from /spl plusmn/1.5 V supplies and occupies 2.02 mm/sup 2/ in 3 /spl mu/m features. In-vivo recordings have shown that the preamplifiers can record single-unit activity 1 ms after the onset of stimulation on sites as close as 20 /spl mu/m to the stimulating electrode. Further artifact suppression is achievable with precise tuning of the low-frequency amplifier cutoff.