학술논문

Relaxation differences using EIS through bronchoscopy of healthy and pathological lung tissue
Document Type
Conference
Source
2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) IEEE Engineering in Medicine & Biology Society (EMBC), 2023 45th Annual International Conference of the. :1-4 Jul, 2023
Subject
Bioengineering
Engineering Profession
General Topics for Engineers
Bronchoscopy
Pathology
Spectroscopy
Lung
Bioimpedance
Frequency measurement
Impedance
Language
ISSN
2694-0604
Abstract
The use of electrical impedance spectroscopy for lung tissue differentiation is an opportunity for the improvement of clinical diagnosis. The aim of this work is to distinguish among different lung tissue states by evaluating the differences among impedance spectrum parameters between two separate frequencies (15 kHz and 307 kHz) in the beta dispersion region. In previous studies we have used single frequency measurements for tissue differentiation. Differences (P < 0.05) are found between those tissues that undergo an increase in tissue density (neoplasm and fibrosis) and those tissues that lead to tissue destruction (emphysema). Electrical impedance spectroscopy shows its utility for lung tissue differentiation for diagnosis improvement among pathologies with different tissue structure. Further studies are necessary for the differentiation among those tissue states that are more similar to each other.Clinical Relevance— Expand the diagnostic tools currently available in bronchoscopy by using minimally-invasive bioimpedance measurements to differentiate between lung patterns.