학술논문

A nonparametric reconstruction and its matrix implementation for the diffusion orientation transform (DOT)
Document Type
Conference
Source
3rd IEEE International Symposium on Biomedical Imaging: Nano to Macro, 2006. Biomedical Imaging: Nano to Macro Biomedical Imaging: Nano to Macro, 2006. 3rd IEEE International Symposium on. :85-88 2006
Subject
Bioengineering
Computing and Processing
Signal Processing and Analysis
US Department of Transportation
Image reconstruction
Image resolution
Magnetic resonance imaging
Microstructure
Reconstruction algorithms
Surface reconstruction
Visualization
Computational modeling
Robustness
Language
ISSN
1945-7928
1945-8452
Abstract
The diffusion orientation transform (DOT) enables the computation of orientational probability profiles from high angular resolution diffusion-weighted magnetic resonance imaging data, making it possible to map connectivity information even in regions with complex microstructure. The initial formulation of the DOT has yielded probabilities in terms of spherical harmonics. In this paper, an alternative reconstruction method is introduced that makes it possible to directly compute the probabilities. The proposed reconstruction effectively combines the reconstruction and surface estimation steps in the visualization of the probability profiles. A matrix formulation is proposed that simplifies the implementation of the DOT method. The simulation as well as experimental results demonstrate the accuracy and robustness of the approach.