학술논문

Albumin-containing solutions equalize quantum yields of porphyrinic photosensitizers
Document Type
Conference
Source
2018 International Conference Laser Optics (ICLO) Laser Optics (ICLO), 2018 International Conference. :597-597 Jun, 2018
Subject
Photonics and Electrooptics
Power, Energy and Industry Applications
Fluorescence
Optical buffering
Medical treatment
Biomedical optical imaging
Optical sensors
Oncology
Laser applications
Biophotonics
Photochemistry
Language
Abstract
Fluorescent and singlet oxygen quantum yields of chlorin-based photosensitizer Photoditazin TM were compared with those of porphyrin-based preparations in the environment of phosphate buffer and albumin. The albumin addition reduced both fluorescence and sensitizing properties of all the agents under study, equalizing quantum yield values of chlorin-based and porphyrin-based preparations. Complex formation between albumin and agent molecules was supposed to be the reason of the effect.