학술논문

A Comparison of Computational Approaches in the Molecular Identification of Pathogenic Organisms
Document Type
Conference
Source
2012 IEEE Second International Conference on Healthcare Informatics, Imaging and Systems Biology Healthcare Informatics, Imaging and Systems Biology (HISB), 2012 IEEE Second International Conference on. :73-73 Sep, 2012
Subject
Communication, Networking and Broadcast Technologies
Computing and Processing
Bioengineering
Components, Circuits, Devices and Systems
Organisms
Medical diagnostic imaging
RNA
Informatics
Educational institutions
Databases
Language
Abstract
Molecular based identification of pathogenic organism is becoming a routine procedure in many diagnostic laboratories. Ribosomal RNA is particularly the most popular choice for this purpose. Although, other targets such as ¡®cytochrome b', ¡®rpoB' and ¡®actin' are highly effective, they have not been extensively used. This could be due to the lack of effective data collection method. We used sequence based exhaustive search of public sequence database to obtain all target sequences. This approach is currently being extended to collect such molecular targets for Nocardia and other slow growing medically important organism.