학술논문

Vitamin D and the Kidney: Two Players, One Console
Document Type
article
Source
International Journal of Molecular Sciences, Vol 23, Iss 9135, p 9135 (2022)
Subject
calcium
cardiovascular disease
cholecalciferol
chronic kidney disease–mineral and bone disorder
fibroblast growth factor 23
kidney transplantation
Biology (General)
QH301-705.5
Chemistry
QD1-999
Language
English
ISSN
1422-0067
1661-6596
Abstract
Vitamin D belongs to the group of liposoluble steroids mainly involved in bone metabolism by modulating calcium and phosphorus absorption or reabsorption at various levels, as well as parathyroid hormone production. Recent evidence has shown the extra-bone effects of vitamin D, including glucose homeostasis, cardiovascular protection, and anti-inflammatory and antiproliferative effects. This narrative review provides an overall view of vitamin D’s role in different settings, with a special focus on chronic kidney disease and kidney transplant.