학술논문
COVID-19 in congenital heart disease (COaCHeD) study
Document Type
article
Author
Ashish Chikermane; Konstantinos Dimopoulos; Michael A Gatzoulis; Sonya V Babu-Narayan; Zdenka Reinhardt; Natali AY Chung; Paul F Clift; Dirk Wilson; Petra Jenkins; Rachel Knowles; Bernadette Khodaghalian; Benjamin Smith; Owen Miller; Umar Mahmood; Heba Nashat; Aoife Cleary; John M Simpson; Clive Lewis; Catherine Head; Sian Chivers; Tara Bharucha; Dominic Hares; Piers EF Daubeney; Caroline B Jones; Milos Prica; James Anthony; Victoria Jowett; Antonia Hardiman; Frances A Bu'Lock; Tristan KW Ramcharan; Jennifer Shortland; Andrew Tometzki; David S Crossland; Leila Rittey; Olga Panagiotopoulou; Muhammad Najih L
Source
Open Heart, Vol 10, Iss 2 (2023)
Subject
Language
English
ISSN
2053-3624
Abstract
Background COVID-19 has caused significant worldwide morbidity and mortality. Congenital heart disease (CHD) is likely to increase vulnerability and understanding the predictors of adverse outcomes is key to optimising care.Objective Ascertain the impact of COVID-19 on people with CHD and define risk factors for adverse outcomes.Methods Multicentre UK study undertaken 1 March 2020–30 June 2021 during the COVID-19 pandemic. Data were collected on CHD diagnoses, clinical presentation and outcomes. Multivariable logistic regression with multiple imputation was performed to explore predictors of death and hospitalisation.Results There were 405 reported cases (127 paediatric/278 adult). In children (age