학술논문

Photodegradation of the Antibiotic Penicillin G in the Aqueous Solution using UV-A Radiation
Document Type
article
Source
علوم بهداشتی ایران, Vol 1, Iss 3, Pp 43-50 (2013)
Subject
Antibiotic
Penicillin G
UV-A Radiation
Photodegradation
Removal
Aqueous Solution
Medicine (General)
R5-920
Language
English
ISSN
2322-553X
2322-4797
Abstract
Background and purpose: Highly consumption of antibiotics and their entrance into the environment has increased concerns all over the world. These compounds enter to the environment through an incomplete metabolism and a considerable amount of them cannot be removed using usual waste filtration systems. Therefore, the present study aimed to investigate the feasibility of using ultraviolet radiation (UV-A) to remove penicillin G (PENG) from aqueous phase and determining its removal efficiency. Materials and Methods: The experiments were carried out in the batch mode. The samples were assessed in a 2-liter reactor. In order to investigate the effect of UV-A radiation on the removal rate of antibiotic penicillin G (PENG), the following parameters were studied. Three concentration levels of PENG antibiotic (10,25,and 45 mg/l) were exposed to UV-A at three pH levels (3,7,11) and were evaluated at four reaction times (30,60,90, and 120 min). Antibiotic penicillin G (PENG) was determined using HPLC instrument (Waters YL9100,USA) and results analyzed using factorial design software. Results: The finding demonstrated that antibiotic removal rate increased by decreasing pH and decreasing the initial concentration of antibiotic and increasing contact time. The maximum rate of penicillin G removal occurred in acidic pH (pH=3) is as much as 38%. All of the variables in the process have been statistically significant effect (p