학술논문
PU.1-c-Jun interaction is crucial for PU.1 function in myeloid development
Document Type
article
Author
Source
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Subject
Language
English
ISSN
2399-3642
Abstract
The transcription factor PU.1 recruits c-Jun as a co-activator to promoters without AP-1 binding sites, and mice with point mutations in PU.1 that disrupts the interaction between PU1 and c-Jun have defects in PU.1 dependent blood lineages, including macrophages and B cells.