학술논문

The epidemiology and detectability of asymptomatic plasmodium vivax and plasmodium falciparum infections in low, moderate and high transmission settings in Ethiopia
Document Type
article
Source
Malaria Journal, Vol 20, Iss 1, Pp 1-10 (2021)
Subject
Plasmodium infection
Elimination
Asymptomatic
Transmission
nPCR
Detectability
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Language
English
ISSN
1475-2875
Abstract
Abstract Background As countries move to malaria elimination, detecting and targeting asymptomatic malaria infections might be needed. Here, the epidemiology and detectability of asymptomatic Plasmodium falciparum and Plasmodium vivax infections were investigated in different transmission settings in Ethiopia. Method: A total of 1093 dried blood spot (DBS) samples were collected from afebrile and apparently healthy individuals across ten study sites in Ethiopia from 2016 to 2020. Of these, 862 were from community and 231 from school based cross-sectional surveys. Malaria infection status was determined by microscopy or rapid diagnostics tests (RDT) and 18S rRNA-based nested PCR (nPCR). The annual parasite index (API) was used to classify endemicity as low (API > 0 and